Knowledge-based translational medicine is a rapidly growing discipline in biomedical research and aims to expedite the discovery of new diagnostic tools and treatments by using a multi-disciplinary, highly collaborative, "bench-to-bedside" approach. Large amounts of multi-omics, imaging (medical and molecular) and clinical data can now be captured for given patient populations. In addition to the challenges of data curation and harmonisation, new computational methods are required to identify molecular signatures that suggest disease subtype. These signatures may be predictive of outcome or progression, and impact on disease management by suggesting personalised therapeutic strategies for patients. Such approaches will further the development of a new taxonomy of disease.
In the TransMed COSI meeting, we will explore the current status of computational biology approaches within the field of translational medicine.
Information of previous TransMed meeting(s) can be found here.
Link to the ISMB/ECCB 2019 website is: here
- Proceedings Submission Deadline: Monday, January 28, 2019. Detail information.
- The TransMed COSI meeting will take place on July 21th-25th, 2019, during the ISMB/ECCB 2019, Basel, Switzerland.
Topics of interest
Topics of interest include, but are not limited to:
- Clinical and molecular data storage and integration infrastructure, including: data warehousing for translational medicine, multi-‘omics and clinical data integration, data visualization in translational medicine
- Curation and harmonization of clinical, ‘omics and imaging data, including: standards and ontologies in translational medicine, biomedical text mining and semantic representation
- Data analytics for patient stratification, biomarker and target discovery, including: disease subtype discovery, Electronic Health Records integration, translational imaging, multi-scale modelling, high performance and cloud computing in translational medicine, mathematical modelling for disease processes, pathways and networks
- Computational approaches for target selection and drug discovery, including: druggability assessment and target selection, polypharmacology, drug reuse, chemical library design, virtual screening technologies, drug discovery enabler pipelines and databases, chemical tool analysis.
- ADME/PK and Tox models, including: databases and modeling approaches for ADME and PK, machine learning approaches to predicting toxicity, modeling of pharmacokinetics to man and model organism utility models.
- Translational Medicine Informatics Applications/Case Studies, including: Next generation sequencing annotation and biomedicine applications, clinical data integration and application.
Isaac Kohane, Department of Biomedical Informatics, Harvard Medical School
Keynote title: Five ways computational biologists can accelerate medicine
Charles Mayo, University of Michigan
Bissan Al-Lazikani, The Institute of Cancer Research
Keynote title: Harnessing Big, Multidisciplinary Data to Inform Cancer Medicine
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Authors are invited to submit abstracts (1 page) for presentations and posters by TBD, 2019. Acceptance notification will be sent out by TBD, 2019.
For proceedings submission the deadline is Monday, January 28, 2019
Please use the [TBD EasyChair] submission system: TBD .
- Detail information can be found: here.
The TransMed COSI meeting will take place on July 21th-25th, 2019, during the ISMB/ECCB 2019, Basel, Switzerland.
We would like to thank our sponsors:
- Luxembourg Centre For Systems Biomedicine (LCSB)
- University of Luxembourg
- ITTM S.A.
for their kind support:
Please follow the registration page on the ISMB website: TransMed COSI Registration.
Venkata Satagopam, Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg
Bissan Al-Lazikani, The Institute of Cancer Research, London, UK
Reinhard Schneider, Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg
Maria Secrier, University College London, UK
Wei Gu, Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg
Mansoor Saqi, King’s College London, UK
Irina Balaur, European Institute for Systems Biology and Medicine, Lyon, France
Programme committee (alphabetical order)
Xuefeng Cui, Tsinghua University, China
Xiaoke Hao, Hebei University of Technology, China
Chaochun Wei, Shanghai Jiao Tong University, China
If you have any questions, please do not hesitate to contact us: firstname.lastname@example.org.
Google Groups: TransMed2019 Google Group
The current TransMed logo was designed by Belinda Hanson.
The previous TransMed logo was designed by Alexandre Pellet, www.alexandrepellet.com.